Les mordus de Paris(1965)

Paris is a city where effervescence is dangerous for city dwellers, who have become nothing more than "nervous machines". Two eminent psychiatrists, one French and one American, decided to administer a sedative to all Parisians, proceeding by arrondissement, which they injected in single, double or triple doses. Soon, the whole of Paris was injected. Calm, good humor and kindness returned, but 11 refused to be treated and remained the only Parisian not to have been treated.